What's Included
Your Stack
MOTS-c
A peptide your mitochondria make during exercise. It flips on the same metabolic switch a hard workout does, telling your cells to burn fuel more efficiently and use energy better. Think of it as the signal that says "run cleaner."
NAD+
The coenzyme your mitochondria literally cannot make energy without. Levels drop as you age, and the whole production line slows with it. Restoring NAD+ is like restocking the raw material the plant runs on.
SS-31
It targets the inner membrane of the mitochondria, steadies the structure where energy is made, and cuts down the "exhaust" (oxidative stress) that wears cells out over time. It keeps the plant running clean.
DSIP
Energy isn't only produced, it's restored, and that happens in deep sleep. DSIP supports the deep, restorative stages of sleep so your body actually rebuilds overnight instead of just clocking hours.
What you can realistically expect
Nobody should promise you a switch flips on day one. Here's the honest version, based on how these compounds tend to work.
First 1 to 2 weeks: Many people notice steadier daytime energy and, if DSIP is working for them, deeper sleep and easier mornings first.
Weeks 4 to 6: This is where the mitochondrial work tends to show up: better stamina, less of a crash after exertion, fewer "hit the wall" afternoons.
Ongoing: The protective, longevity side (the SS-31 and NAD+ work) is cumulative. It's playing a long game with your cells, not a quick stimulant high.
The point worth repeating: this isn't a stimulant. It won't feel like an energy drink. It feels like the floor under your energy rising over time. Consistency matters more than any single dose.
Why a stack beats a single energy peptide
You could take just one of these. Plenty of people do. But energy isn't a single lever, it's a loop: produce, protect, restore, repeat.
Take only NAD+ and you've restocked the fuel, but the machinery is still aging and you're still not sleeping deeply. Take only DSIP and you sleep better, but you wake up to the same underpowered cells. Each one alone leaves a gap, and the gap is what you feel at 3 p.m.
The bundle closes the loop. Production (MOTS-c), raw material (NAD+), protection (SS-31), and restoration (DSIP), working the way your energy actually works: as a system, together.
Energy Bundle FAQs
Will this feel like a stimulant or an energy drink?
No, and that's the point. The Energy Bundle doesn't spike and crash like caffeine. It works on how your cells produce and restore energy, so what most people describe is a steadier baseline that builds over weeks: fewer crashes, better stamina, easier mornings.
If you want a jolt in 30 minutes, this isn't that. If you want the floor under your energy to rise, this is the approach.
How soon will I notice anything?
Timelines vary. Many people notice steadier daytime energy and deeper sleep within the first one to two weeks, with bigger stamina and recovery changes showing up around weeks four to six as the mitochondrial effects build.
The protective, longevity side is cumulative and plays out over months. Consistency beats intensity here.
What does each of the four actually do?
MOTS-c signals your cells to use energy more efficiently, the same switch exercise flips.
NAD+ is the coenzyme your mitochondria need to produce energy at all.
SS-31 protects the mitochondrial machinery and reduces oxidative stress.
DSIP supports the deep sleep where your body recharges. Three power and protect the cellular power plant; one restores it overnight.
Can I take this with metformin or other blood-sugar medication?
This is an important one to flag with your provider. MOTS-c works through AMPK, the same pathway as metformin and some other insulin-sensitizing drugs, so combining them can have an additive effect on blood sugar.
It isn't automatically a problem, but it's exactly why a provider reviews your medications first and personalizes your protocol. Tell us everything you take.
When should I take each one?
Your provider sets the schedule, but the general logic is intuitive: the energizing pieces (MOTS-c especially) are usually taken earlier in the day so they don't interfere with sleep, while DSIP is taken in the evening to support your night. We map the exact timing to your routine.
Do I have to inject these? Does it hurt?
Most of these are given as small subcutaneous injections with a very fine needle, similar to other peptide protocols, and the most common side effect is minor: a little redness or tenderness at the site.
Your care team walks you through technique so it's quick and nearly painless, and shows you how to rotate sites to keep it comfortable.
Is this just for athletes, or for tired people too?
Both. Athletes use stacks like this for stamina, output, and recovery, but plenty of people come to it simply because they're worn down: busy professionals, parents, anyone whose energy isn't what it was and who's tired of caffeine as the only answer.
It pairs best with the basics actually working: real sleep, real food, some movement.
What are the possible side effects?
These compounds are generally well tolerated, but that does not mean side-effect free.
The most common is mild injection-site reaction (redness, swelling, tenderness). Some people notice mild fatigue or appetite changes when starting MOTS-c as the body adjusts, and rarely, blood-sugar dips, especially when combined with fasting or diabetes medication. DSIP may leave some people groggy if timed poorly.
If side effects are persistent or severe, contact your provider.
Who should not take the Energy Bundle?
It's not for anyone pregnant or breastfeeding. If you take medication for blood sugar, or you have a metabolic, heart, or other chronic condition, your provider needs to review fit before you start, because some of these compounds interact with those systems.
The intake and provider review exist precisely to catch this.
