
DSIP Nasal Spray
DSIP Nasal Spray is a synthetic peptide formulation of Delta Sleep-Inducing Peptide, a molecule naturally present in the brain and known for its role in regulating sleep cycles and stress response. Researchers have explored DSIP for its potential to improve deep sleep quality, stabilize circadian rhythm, and support recovery from stress or fatigue.
Nasal Spray Strength and Volume
Designed for rapid absorption and portability.
Strength: 10 mg (10,000 mcg)
Concentration: 1 mg/mL
Actuation Rate: 100 mcg per spray
Spray Volume: 0.1 mL per spray
Total Volume: 10 mL
⚠️ Important Disclaimer
For Research Use Only. Not for human consumption or therapeutic treatment.
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DSIP Nasal Spray
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Key Highlights
Promotes Deep, Restorative Sleep
Induces delta-wave sleep, enhancing recovery, mood, and cognitive function.
Balances Stress Hormones
Helps modulate cortisol levels to support resilience against stress and fatigue.
Supports Hormonal Health
May promote the natural release of luteinizing hormone (LH) and growth hormone (GH).
Pain & Inflammation Relief
Shown to reduce chronic or persistent pain in research models.
Aids Detox & Withdrawal Studies
Explored for its potential to ease alcohol and drug withdrawal symptoms.
Long-Lasting Sleep Benefits
Effects can extend beyond one night, improving overall sleep quality and rhythm.

What Is DSIP Nasal Spray?
DSIP (Delta Sleep-Inducing Peptide) is a naturally occurring peptide hormone first discovered in the hypothalamus. It helps regulate the body’s internal clock, promote delta-wave sleep, and balance neuroendocrine functions.
When formulated as a nasal spray, DSIP provides a fast-acting and accessible approach for research into sleep restoration, stress adaptation, and hormonal balance.

Why Choose DSIP Nasal Spray?
Researchers select DSIP Nasal Spray for its efficient delivery and consistent research outcomes. Unlike injectable formulations, the nasal spray allows direct central nervous system access through the olfactory pathway—ideal for exploring neurological and circadian mechanisms.
Each vial is produced under ISO-certified, cGMP-like conditions, tested for purity, potency, and stability. This ensures reliable performance across studies related to sleep deprivation, chronic stress, neurohormonal regulation, and recovery biology.
DSIP Nasal Spray FAQs
How does the nasal spray differ from injectable DSIP?
The nasal spray provides a faster onset and non-invasive administration, potentially enhancing brain delivery compared to injections.
What does DSIP stand for?
DSIP stands for Delta Sleep Inducing Peptide, referring to its ability to promote delta-wave activity during deep sleep.
How does DSIP work?
It acts on multiple brain regions and hormonal pathways to regulate circadian rhythms, promote relaxation, and encourage delta-wave sleep.
How long do DSIP’s effects last?
In some research reports, a single dose has shown residual sleep-improving effects for several nights.
Can DSIP be combined with other peptides?
Yes. It’s sometimes paired with peptides that influence relaxation, recovery, or hormone regulation, such as GHRP-2 or CJC-1295.
What are the main research applications of DSIP?
Common areas include sleep disorders, stress regulation, pain management, and hormonal recovery studies.
What are the primary effects or benefits reported for DSIP?
Some of the noted effects in research and early human/animal studies include:
- Increased “sleep pressure” and promotion of slow-wave (delta) sleep
- Restored or improved sleep architecture (efficiency, fewer awakenings)
- Modulation of cortisol and stress response
- Support for hormonal balance — e.g. promoting LH, GH, or suppressing ACTH/cortisol in some models
- Analgesic (pain-reducing) effects in small clinical or animal trials
- Potential support in alcohol or opioid withdrawal symptom relief in older clinical reports
Is DSIP safe? What side effects have been reported?
DSIP has historically been considered low risk in small human studies. Side effects reported include transient headache, nausea, or vertigo.
How should DSIP be stored or prepared for use?
As with most peptides, DSIP typically comes as a lyophilized powder and must be reconstituted in a sterile, appropriate diluent (e.g. bacteriostatic water) before use. After reconstitution, it should be stored under cold conditions (e.g. 2–8°C).
Who might benefit most (or least) from DSIP in research?
Because the strongest literature exists in sleep disturbance, insomnia, chronic stress, pain, and substance withdrawal, these are common research applications.
However, DSIP is experimental and may not be suitable in settings with hormone-sensitive conditions, or where peptide degradation interactions are possible.

